I went into the darkest depression ever…and I was lacking in energy so much that I had to have 4 naps a day…just to get through the day. Every 4-5 months, very happy with results to date. I started loosing wait and my nerves got bad . –Mood swings I tried to go the route my urologist provide of 50mgs of injectable test weekly. I assure you the comment by this Dr. claiming the post above makes absolutely no sense (I believe it makes no sense to him, because he has zero knowledge on the subject) is dead wrong, and the poster was pretty much right on point with what he said. My urologist has performed 4 biopsies and one prostate MRI over that time, all of them negative. . Patches, gel and spray did not do much for my disposition, energy or overall sense of well being. Started Androgel, felt normal after a couple of weeks. Or does it kick on your bodies natural production? With age, SHBG (Sex hormone-binding globulin) levels increase while FT levels decrease. Further, you have to know about prostate-specific antigen (PSA), problems in the prostate and digital rectal exam. I asked if I could purchase it with cash and they told me that the FDA is not approving this usage anymore but did not provide an option. My last injection was November 2017 and i decided to rest for a quarter and see what the impact is. Potential benefits include improved libido, increased bone mass, and increased sense of well-being. The contents displayed within this public group(s), such as text, graphics, and other material (“Content”) are intended for educational purposes only. Thanks very much for the information provided on this site. This has been pure hell. I was able to pursue my endeavors with the energy provided, I was able to think about running and exercising and then put that thought into action. One more thing that I have experienced from getting injected T is that my testicles have shrunk and they have shrunk quite a good amount. Journal of Clinical Endocrinology and Metabolism 2004;89:2085–98. Gets REALLY expensive in this day and age). Gels are a weak joke. I have administered 10 X the recommended dose with no bad side effects. Also feels like I am doping like a pro-cyclist (hate cheaters) Without it my muscles and joints stiffens so painfully, fuzzy and somewhat depressed, when pushing very hard while exercising the sensations become bizarre and again so incredibly painful — it feels so good after the injection if I had waited too long! College years we did it again and again but not anywhere near the levels of body builders we knew and saw at the gym. The primary hallmark of low testosterone is low sexual desire or libido, but another can be erectile dysfunction, and any man who complains of erectile dysfunction should get his testosterone level checked. My doctor recommended a compounding Pharmacy that made a cream and it was perfect. Currently I am “prescribed” 200mg IM weekly, 1mg of anastrosole weekly to help avoid the conversion to estrogen and 50mcg of HCG twice weekly for cosmetic effects. The gel comes in miniature tubes or in a special dispenser, and you rub it on your shoulders or upper arms once a day. I still haven’t found a answer for my question and that is why is it when my testosterone gets low my face and back breaks out with acne.I get injections every 2 weeks now and after the 8 or 9th day I’m so tired I don’t want to do anything if anyone has anything they could help please send me a email and many thanks to you, Split dosage and inject weekly stops the up and down effect from waiting two weeks for injection. This has been known for years that you must be prepared to control Estrogen. Testosterone undecanoate is a long-lasting ester, and physicians typically try to inject on an every 6 week or 2 month protocol. It can also increase the oiliness of the skin, so that some men get acne or pimples, but that’s quite uncommon, as are sleep apnea and gynecomastia (breast enlargement). I had prostate cancer treated with brachytherapy (internal iodine seed radiation) 20 years ago. Clomid benefits tapering off ... After about a month on clomid therapy, my testosterone went from 150 to 580. Think: when you were teenager: you were active without thinking of ways to be active. They prescribe 50 mgs a week. Muscles seem so much more aware of stiffness. I was lucky it happened after 50 years of memories ’cause I missd and have problems recalling the last seven years that I was on TRT (5 pumps a day of 1.25mgs). I am 27 yrs and on Cernos depot( 1000 mg ) shot since 3 years after I was advised by an Andrologist as I was uncomfortable with other injectable esters due to its roller-coaster behaviour. I am low testosterone 223 after test november 2015 n my doc prescribed me clomiphene 25mg every day for 90 days n i wanna be biological father is it good choice to take this medication for low T please i help me. Nevertheless, the risk exists, so we want to be careful about giving testosterone to men who already have a high hematocrit, such as those with chronic obstructive pulmonary disease, or those who have a red-blood-cell disorder. That should be all you need to reduce the estrogen in your body.,my husband takes 1mg of Anastrozole 2 times a week. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. Not 500, but 5! Not a bad thing but sometimes it takes way too long. That universla health care system is a scam. ang="en-US" prefix="og: http://ogp.me/ns#">. Last time fasting it was 53 but was 50 a few days later when checked at 2:00pm not fasting. Andy – If you take testosterone, your hypothalamus will notice an abundance of testosterone in your system and will instruct your pituitary gland not to send LH and FSH to your testicles. Journal of Urology 2003;169:1670–5. Before I knew it, at about month I was at 1500 count. How is it that women for many years have had HRT available and it is common place and acceptable for them? My urologist refuses to resume any HRT as my total testosterone is 701 immunoassay. DON’T START TRT…unless you’re dealing with a doctor who knows what the hell they are prescribing. I’m 25 years old and have been on TRT since 8th grade. My total T fluctuates between 500 and 1000 and my E2 has been staying under 30 with the help of Arimidex 0.5 mg every 3.5 days. Had a great improvement on everything I was having issues plus just a lot happier. My symptoms: –Extreme fatigue I would wager that given T without anastrozole and having belly fat, that aromatase enzyme converted T to estrogen and that is why clots developed and why they felt worse instead of better. WHY? On testosterone replacement for the past 3/4 years using an injection (self administered) every 10 to 15 days intervals of 200mg/mL at 0.8ML even though prescribed once a week. (It became a standard therapy that we still use today for men with advanced prostate cancer. So I go in for my scheduled injection and they tell me there out of testosterone . I felt great at both levels. Journal of Clinical Endocrinology and Metabolism 2004; 89:4789–96. I was cut of treatments immediately. I am planning to take TRT with Testosterone mix called SUSTANON 250 mg per week and HCG 5000 IUs twice a month. If you are taking shots or gel or cream and feel little to no effect even though it’s technically raised your T blood ranges, you now have an multiple answers for why you little to nothing or feel even worse. Aromason will do same but clomid is more potent. AC – go on some of the bodybuilding forums,they have sources there from whom you can buy generic Clomid relatively cheaply. There were two sites with PIN (one with outpouching and one was focal). The one side effect that no one talks about is psychological for me. When you start TRT, you want to be mobile/active (maybe again), don’t forget this when you stop TRT. Estrogen is usually high. More over will I become sterile , I have a young wife and we may have more kids. Highlights the importance of an appropriate diagnostic work up and monitoring plan. Then he gave me the injection of 200mg test . Reluctantly moved to Big City, small house. My weight increased a .little since beginning therapy. So far so good. It’s pretty worth enough for me. At age 63 started an exercise program. Strange thing is I think I have found a compounding pharmacy in Houston Texas that will fill this Rx. contact us at ReGenesis HRT. After spilling my guts to my doctor we decided upon the gel. Now I am 1350 total and 125 free. But no one quite agrees on a number. To the rest of us I highly recommend that you research as much as possible before using out of state clinics. . I am sorry but if you are a doctor you really are making it obvious that it’s possible for doctors to know nothing about this problem.What kind of Doctor are you? Any thoughts or suggestions would be greatly appreciated. I would be happy paying the money if i could cut the cost, and still feel safe, pay for testing? and i can not do my studies or anything properly that i want to do. I found my own source and have been on top of the world for 6 years. It seems that just nobody knows for sure. I see this is an older thread, but still very appropriate. What forms of testosterone-replacement therapy are available? Given the choice between giving up my prostate or giving up my T? My testicles reduced their size to half it´s original size, my libido is almost zero. Clinical Review 171: The Rationale, Efficacy and Safety of Androgen Therapy in Older Men: Future Research and Current Practice Recommendations. I feel once a week injection is what it will take to get feeling good again. I think I’ve had low testosterone my entire life, though I’ve always had a healthy sex drive I was always tired and always sensed something was wrong although I sought out treatment at the doctor’s but just could never quite pinpoint what the problem was. CC works. Also have less sensitivity during sex and it takes longer to orgasm. What effect would testosterone replacement have on stimulating the bone marrow to produce reticulocytes and increase red cell production in a patient with aplastic anemia. Completely out now for close to a week and have been working for five weeks trying to get again. I look better than 90% of the 25 year olds I see in the gym. Very good indeed. It just extends the time for recovery and the time you will feel crappy. Please note: If you have a promotional code you'll be prompted to enter it prior to confirming your order. how long does it take for T level go back to base line after stopping treatment? T replacement gives it 3 weeks later I finally got a appt. Additionally, you may have adult onset gH deficiency. Androgel could only bring my T level in the 250 range. My mind, body, and spirit were one. And I trust the test results more than her “belief”. If it is applied in gel format (i.e. The HGH hormone – Your pituitary gland produces this substance. It stimulates the growth of the genitals at puberty, plays a role in sperm production, fuels libido, and contributes to normal erections. I am over weight with a fat belly. Enter search terms and tap the Search button. Neurology 2001;57:80–88. See, a TT of 1000 of a young man won’t be the same as the TT of 1000 for an older man with high SHBG levels, because the FT level of the older man will likewise be well below, even though they have the same TT. What is your opinion of using depo-testosterone injections on women? So, I’m no longer worried that giving testosterone to men will make their hidden cancer grow, because I’m convinced that it doesn’t happen. I am not sure what to take. Testosterone is the single most important hormone in a male’s body. In 2014 my levels were 16.5 and in 2016 that dramatically reduced to a score of 10.4. Don’t do it – Testosterone supplements cause cancer. Law suits are out about T and blood clots. I am 44 and have had a complete hyserectomy. The prostate has shrunk to a much smaller size and the PSA has been undetectable for 20 years. The issue is the type of hormone used and doctors not knowing what they are doing. For example, testosterone can increase the hematocrit, the percentage of red blood cells in the bloodstream. Enough already!!!! In the past, because men die of heart attacks more often than women and men have more testosterone, the fear has been that testosterone causes heart problems. I wont mention names. In its 2004 report, the Institute of Medicine (IOM) committee studying the need for clinical trials of testosterone-replacement therapy noted that only 31 placebo-controlled studies had been done in older men, with the largest one enrolling just 108 participants. After trying shots and not liking the roller coaster effect, I switched to gels. I do not intend to spill my guts about symptoms or values on here as it has already been done so many times over. Saw urologist last week. Benefits are also good. Journal of Clinical Oncology 2000;18:847–53. But if all of those results are normal, then we can initiate testosterone therapy. PMID: 11337297. I’ve had low testo in the winter for the last 10 years, with the lowest values around april (live in the north). However an endocrinologist here refuses to consider TRT claiming serum testosterone results of 10.7 nmol/L are not sufficiently low to begin treatment or even a trial to see if this would improve the osteoporosis. Eric 65 yrs old. My doctor and I agree that we need to another blood test before making a decision as to what we may or may not need to do. My blood has always been quick to coagulate. I feel like I did when I was 30 including a very healthy dream cycle about my wife. I noticed that when I take the injection my normal resting heart rate is about 61 beats a minute, on the day of the injection it goes up to about 84 BPM. I’ll get rid of the prostate in a heartbeat. All the worries are unwarranted and debunked. As with all things there is some bad with the good. What recommendations do you have for monitoring once testosterone therapy begins? My energy level have increased and my muscle mass has also increased, so I have positive results. I’ve talked to a endocrinologist and urologist who said they would have never started me on it. It worked great but having kids around I was worried about it affecting them so we switched to in ejections taken every 2 weeks of cypionate 200mg and my wife helps me with that at home and I never stray from the regime . [For specifics on various formulations, see table below.]. Smokers may have higher risk of brain aneurysm, Attention deficit/hyperactivity disorder (ADHD) in children, Testosterone enanthate (Delatestryl) and testosterone cypionate (Depo-testosterone) injections, 200 mg every 2–4 weeks (testosterone enanthate); 100 or 200 mg every 2–4 weeks (testosterone cypionate), Peaks and valleys in blood testosterone levels; frequent office visits for injections, May be less irritating to skin than nonscrotal patches, Scrotum must be shaved in order for patch to adhere to skin, Nonscrotal testosterone patch (Testoderm TTS and Androderm), One or two patches/day, depending on strength (2.5–5 mg/patch), Ease of application; mimics normal daily rise and fall of testosterone, May need two patches a day; can cause skin irritation, Ease of application; generally well tolerated by skin, Not all patients absorb it well; potential to transfer to others through skin-to-skin contact soon after application; relatively expensive, Methyltestosterone (Testred) and fluoxymesterone (Halotestin) pills, 30-mg tablet twice a day; applied to gums, More effective at raising testosterone levels than skin patches, May cause gum or mouth irritation, pain, and tenderness; bitter taste, Injectable testosterone undecanoate (Nebido/Aveed), 1,000 mg to start; 1,000 mg at 6 weeks; 1,000 mg every 12 weeks thereafter, Needs to be administered only four times a year, Under FDA review and not currently available in the United States, low levels of testosterone in the blood (less than 300 ng/dl), a nodule on the prostate that can be felt during a DRE, a PSA greater than 3 ng/ml without further evaluation, a hematocrit greater than 50% or thick, viscous blood. 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